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Dernières publications
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
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Chiffres clés
134
Publications avec texte intégral
Open Access
52 %
Mots clés
Humans
Male
Myotonic dystrophy type 1
Acute coronary syndrome
Exercice
Muscular dystrophy
Autophagy
CONGENITAL MYATHENIC SYNDROME
RNA splicing
Exercise
Genotype phenotype correlation
PacBio
Skeletal muscle
Astrocytes
Dystrophie Myotonique
Duchenne muscular dystrophy
Transcriptomics
ACETYLCHOLINESTERASE
Myelin
Oligodendrocyte
Myotonic dystrophy mouse models
Myotonic Dystrophy
Acetylcholinesterase knockout mouse
Myotonic dystrophy
Cell penetrating peptide
GABA
Aging
Expression
Dilated cardiomyopathy
KNOCKOUT MICE
DMPK
Glutamate
Gene therapy
MBNL
Brain dysfunction
Myotonic Dystrophy type 1
DMSXL mice
Desmin
Cell model
Long read sequencing
Astrocyte
Neuron
ARN
In vivo
Quantitative microdialysis
Glucocorticoids
Heart failure
Acetylcholinesterase deficiency
Mice
Lc3
Glial cells
Hypoxia
Gene editing
Fibrosis
BIOLOGIE MOLECULAIRE
Trinucleotide Repeat Expansion
Maximal force
CRISPRi
GSK3
Centronuclear myopathy
CMS
Thérapie génique
Antisense oligonucleotides
Dynamin 2
Dystrophin
Transgenic mouse model
Mouse models
RNA interference
Central nervous system
CTG repeat instability
Antisense oligonucleotide
Glucocorticoid-receptor
Myostatin
Trinucleotide repeat expansion
Intermediate filament
CTG repeats
Brain
PCR
Cardiac muscle
AAV
Mouse model
Dystrophie myotonique
Motoneuron
Cytoskeleton
Transgenic mouse
Alternative splicing
CTG repeat contractions
Cell culture model
Myotonic Dystrophy Type 1
Muscle
Knockout
DM1
Animals
CRISPR/Cas9
Oligodendrocytes
Heart
Therapy
Gene Therapy
Diaphragm
RNA biology